List of publications

A Human Gut-Liver-Brain physiomimetic approach to parse links between microbial metabolites and neurodegenerative diseases. Science Advances. 2021; 7(5):eabd1707.
Trapecar M, Wogram E, Svoboda D, Omer A, Lungjangwa T, Communal C, Phabmixay P, Velazquez J, Schneider K, Wright CW, Mildrum S, Hendricks A, Butty V, Levine S, Lee M, Lauffenburger D, Trumper D, Jaenisch R, Griffith LG.

Gut-Liver physiomimetics reveal paradoxical modulation of IBD-related inflammation by short-chain fatty acids. Cell Systems. 2020; 10(3):223-239.e9.
Trapecar M, Communal C, Velazquez J, Maass CA, Huang Y, Schneider K, Wright CW, Eng G, Yilmaz O, Trumper D, Griffith LG.

Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development. Altex. 2020; 37(3):365-394.
Marx U, Akabane T, Andersson TB, Baker E, …Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A.

Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells. Journal of Virology. 2020; 95(2):e01331-20.
Yukl A, Khan S, Chen T, Trapecar M, Wu F, Xie G, Telwatte S, Fulop D, Pico AR, Laird GM, Ritter KD, Jones NG, Lu CM, Siliciano R, Roan N, Milush J, Somsouk M, Deeks S, Hunt P, Sanjabi S.

Low expression of RNA sensors impacts the innate immune response to Zika virus infection in the lower female reproductive tract. Nature communications. 2019; 10(1):4344.
Khan S, Lew I, Wu F, Fritts L, Fontaine K, Tomar S, Trapecar M, Shehata H, Ott M, Miller CJ, Sanjabi S.

B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection. Mucosal Immunology. 2018; 11(4):1158-1167.
Trapecar M, Khan S, Cohn BL, Wu F, Fontaine KA, Ott M, Sanjabi S.

HIV-1 Transcriptional Activity and Infectious Burden in Peripheral Blood and Gut-Associated CD4+ T cells Expressing CD30 and CD32. PLOS Pathogens. 2018; 14(2):e1006856.
Hogan L, Vasquez J, Hobbs K, Hanhauser E, Aguilar-Rodriguez B, Hussien R, Thanh C, Gibson E, Carvidi A, Smith L, Khan S, Trapecar M, Sanjabi S, Somsouk M, Stoddart C, Kuritzkes D, Deeks S, Henrich T.

Beneficial effects of water-soluble chestnut (Castanea sativa Mill.) tannin extract on chicken small intestinal epithelial cell culture. Poultry Science. 2018; 97(4):1271-1282.
Brus M, Gradisnik L, Trapecar M, Skorjanc D, Frangez R.

An Optimized and Validated Method for Isolation and Characterization of Lymphocytes from HIV+ Human Gut Biopsies. AIDS Research and Human Retroviruses. 2017; 33(S1):S31-S39.
Trapecar M, Khan S, Roan N, Chen TH, Telwatte S, Deswal M, Pao, Somsouk M, Deeks SG, Hunt PW, Yukl, S, Sanjabi S.

Differentiating Immune Cell Targets in Gut-Associated Lymphoid Tissue for HIV Cure. AIDS Research and Human Retroviruses. 2017; 33(S1):S40-S58.
Khan S, Telwatte S, Trapecar M, Yukl S, Sanjabi S.

Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication. Journal of Experimental Medicine. 2016; 213(13):2913-2929.
Khan S, Woodruff E, Trapecar M, Fontaine K, Ezaki A, Borbet T, Ott M, Sanjabi S

Single-cell analysis reveals IGF-1 potentiation of inhibition of the TGF-β/Smad pathway of fibrosis in human keratocytes in vitro. Scientific Reports. 2016;6: 34373.
Sarenac T, Trapecar M, Gradisnik L, Slak Rupnik M, Pahor D.

Platelet-rich plasma, especially when combined with a TGF-ß inhibitor promotes proliferation, viability and myogenic differentiation of myoblasts in vitro. PloS One. 2015;1-13.
Kelc R, Trapecar M, Gradisnik L, Rupnik M, Vogrin M.

HUIEC, Human intestinal epithelial cell line with differentiated properties: process of isolation and characterisation. SPRINGER Wiener Klinische Wochenschrift. 2015;1-6.
Gradisnik L, Trapecar M, Rupnik M, Velnar T.

A co-culture model of the developing small intestine offers new insight in the early immunomodulation of enterocytes and macrophages by lactobacillus spp. through Stat1 and Nf-kB p65 translocation. Plos One. 2014;9(1), 1-8.
Trapecar M, Goropevsek A, Gorenjak M, Gradisnik L, Rupnik, M.

Myogenic progenitors and imaging single-cell flow analysis: a model to study commitment of adult muscle stem cells. Journal of Muscle Research and Cell Motility. 2014; 35, 5-6.
Trapecar M, Kelc R, Gradisnik L, Vogrin M, Rupnik M.

Novel metabolic roles of L-arginine in body energy metabolism and possible clinical applications. The Journal of nutrition, health and aging. 2014; 18(2), 213-218.
Kocic H, Langerholc T, Trapecar M.

Improvement of lipid profile by probiotic/protective cultures: study in a non-carcinogenic small intestinal cell model. The New microbiologica. 2014;37(1), 51-64.
Gorenjak M, Gradisnik L, Trapecar M, Pistello M, Pinto Kozmus C, Skorjanc D, Skok P, Langerholc T, Cencic A.

Skeletal muscle derived cell cultures as potent models in regenerative medicine research. Muscle & nerve. 2013;47(4), 477-482.
Kelc R, Trapecar M, Vogrin M, Cencic A.

Natural mineral waters enhance the intestinal health and stimulate anti-inflammatory immune response in functional cell model of a non-cancerogenic human gut. Journal of food research. 2012;1(2), 217-223.
Trapecar M, Goropevsek A, Zbontar Zver L, Cencic A.

Application of gut cell models for toxicological and bioactivity studies of functional and novel foods. Foods. 2012;(1), 40-51.
Trapecar M, Cencic A.

A Novel polymerase chain reaction (PCR) based assay for authentication of cell lines or tissues from human, pig and chicken origin. Journal of bioscience and biotechnology.2012;1(1), 1-7.
Gorenjak M, Trapecar M, Gradisnik L, Skok P, Cencic A.

The Use of a porcine intestinal cell model system for evaluating the food safety risk of Bacillus cereus probiotics and the implications for assessing enterotoxigenicity. APMIS. 2011;119(12), 877-884.
Trapecar M, Leouffre T, Faure M, Jensen H, Granum Pe, Cencic A, Hardy Sp.